pycnogenol benefits dr axe

They were treated with 200 mg of Pycnogenol daily or with placebo. Another 2006 study examined the effects of the antioxidant activity of pine bark extract on oxidative stress, which is thought to be one of the nongenetic factors contributing to ADHD. Additionally, athletes have endured less cramping and muscle pain when using the extract. It may cause side effects such as: Dizziness. Pycnogenol-treated patients had significant improvement in symptoms as well as a reduction in leg swelling as compared to those not receiving treatment. after four weeks of treatment, Pycnogenol-treated patients showed definite evidence of improved in small blood vessel functions and circulation as compared to those not treated. The results of a 2013 animal study suggest that pine bark extract may help to reduce damage to nerve cells following a traumatic brain injury. A study of 147 people found that pycnogenol (100 mg/day) may improve running, push-ups, and sit-ups endurance in recreational athletes over an 8-week training program. Also, be sure to talk with your doctor first if you have an underlying medical condition or take other medications. It had the best results when combined with compression stockings, but worked just as well alone [28]. Tongkat ali is an herbal remedy suggested to treat various ailments, including low testosterone and male infertility. Dr. Eric L. Zielinski is a sought-after natural . That way, your doctor can check on any potential side effects or interactions with medications. A randomized clinical trial of 30 people found that Pycnogenol (150 mg/day) may help heal vein ulcers from surgery and reduce swelling after 3 months of treatment [25]. He later extracted proanthocyanidins from the European coastal pine tree, which he named Pycnogenol.. Chestnut seed extract did not do as well. Researchers suggest this benefit may be due to an increase in glutathione and SOD, two antioxidants that may reduce inflammation and oxidative stress in Crohns [76]. . 2005 - 2023 WebMD LLC. With strict editorial sourcing guidelines, we only link to academic research institutions, reputable media sites and, when research is available, medically peer-reviewed studies. Pycnogenol lotions applied postirradiation reduced this immunosuppression to 22% (0.05% Pycnogenol) and 13% (0.1% Pycnogenol). While the aspirin reduced the risk for cardiovascular disease and colorectal cancer, among other cancers, the risk of gastrointestinal bleeding outweighed those benefits, creating more risks to the body. The staff there can often answer any questions you have and give you more information about specific brands. Pycnogenol has been well-tolerated in most studies performed thus far. This supplement possibly activates the immune system. WebMD does not provide medical advice, diagnosis or treatment. but is for informational and educational purposes alone. In a clinical trial of 116 women, Pycnogenol (60 mg/day) reduced menstrual pain and the need for additional painkillers, taken over 2 cycles. You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition. Potential for allergy when taken orally or used on the skin. For people who have symptoms that are more severe, traditional medicine is probably more effective. However, some of these other pine bark extracts can have different active compounds, which may affect their biological activity. There were 88 in the control group and 81 in the Pycnogenol group. . If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please leave a comment or contact us at [emailprotected]. In the control group, there were five thrombotic events; whereas the Pycnogenol-treated subjects only experienced nonthrombotic, local flare-ups. Consider pine bark extract through a conversation with your physician or a functional medicine doctor. The U.S. Food and Drug Administration (FDA) does regulate dietary supplements; however, it treats them like foods rather than medications. It can also stabilize mast cells, which release histamine and trigger allergic reactions. Pine bark extract comes from the inner bark of the Pinus pinaster tree, most commonly found in Europe. Depending on the extraction process and the source Pinus species used (P. radiata or P. pinaster), the exact composition will vary. The goal of this study was to evaluate if Pycnogenol could prevent deep venous thrombosis (DVT) and superficial vein thrombosis (SVT) in eight-hour flights in 196 subjects at risk of these conditions. It is chronic venous insufficiency, a common disease among people who are obese or elderly and those who lead a sedentary lifestyle. 5) Vein Diseases and Swelling. One study found that Pycnogenol may reduce the activity of the inflammatory enzymes COX1 and COX2, similar to how NSAID drugs work. The top benefits of nattokinase include the following: Regulate blood pressure. Pycnogenol is similar to grape seed extract and cocoa polyphenols as those are the three most common . Another one of its exemplary effects is helping manage blood pressure levels. As I mentioned, pine bark extract is superior when it comes to antioxidants. are clickable links to medically peer-reviewed studies. (2017). A study of 58 people with high blood pressure suggests that even lower doses (100 mg/day) may improve blood vessel health and reduce markers of high blood pressure (endothelin-1) after 12 weeks. Staves Off Infections. Rating: 100%. One way to add some extra flavor and nutrients to your day is by adding prune juice to your diet. But what are its health benefits? Potential benefits of folic acid include a reduced risk of cancer, improved cognitive function, stronger bones, enhanced heart health, better pregnancy outcomes and reduced symptoms of restless legs syndrome. Symptoms of menopausal syndrome, also known as climacteric syndrome, include: hot flashes; chills; headache; and depression. The study provided clear evidence that Pycnogenol does, indeed, offer photoprotection however, it came out even better than expected, showing that it may be used to reduce hyperpigmentation of human skin while improving the skin barrier function and extracellular matrix homeostasis. (6). However, it is also important to see beyond the pyncogenol marketing campaign and understand the possible dangers associated with this natural supplement. This study adds to a body of research showing the benefits of Pycnogenol . All included participants had subclinical cognitive impairment, which looks like typical brain fog [22]. Thus, this powerful extract works as a natural ear infection remedy while improving balance and preventing hearing loss. Note that each number in parentheses [1, 2, 3, etc.] 3. Blood pressure is an important measure of how much blood is pumping from your heart to the rest of your body . It also appeared to improve their attention span, visual motor skills, and concentration. The dosage in most clinical studies varied between 50-360 mg/day. Add to Cart. It has many health benefits, and may help protect against several chronic conditions. You can learn more about how we ensure our content is accurate and current by reading our. Inhibits platelet aggregation like low-dose aspirin. Results showed that one month of Pycnogenol led to a significant reduction of hyperactivity with improvement in attention and visual-motor coordination and concentration, as compared to no positive effects in the placebo group. In another trial, 30 people with type 2 diabetes received a range of pycnogenol doses. The 2012 study on the anti-aging benefits of Pycnogenol is commonly-cited by anti-aging supplement manufacturers. (7). That said, there are some instances where this extract may possibly be effective. Pycnogenol is a patented formulation of Pine Bark Extract which is standardized to 65-75% Procyanidin compounds by weight. (13). 1. Researchers suggest that it may epigenetically turn off genes responsible for joint damage (ADAMTS) as well as reduce inflammation enzymes (MMP3) and cytokines (IL 1-beta) [47, 48]. The most effective blood sugar-lowering dose was 200 mg/day higher doses had no further benefit [33]. Clearer skin, healthier hair there are a lot of claims about the health benefits of biotin. 7. In 7 volunteers, Pycnogenol (300 mg) for 5 days may reduce the activity of a crucial inflammatory gene (NF-B) [53]. Plus, it reduced total and LDL (bad) cholesterol. Chewing gum with Pycnogenol (2.5 mg/piece) for 4 weeks reduced bad breath and mouth bacteria in a trial of 22 people [57]. A trial of 132 people found that Pycnogenol (150 mg/day) may improve risk factors of metabolic syndrome including lowering triglyceride levels, blood pressure, and fasting glucose, decreasing waist circumference, and increasing HDL cholesterol levels [29]. $31.99. DOI: Trebatick J, et al. Commonly called arthritis, osteoarthritis is caused when the cartilage on your joints begins to wear down. (2006). (2013). A popular variety is the pinus maritime or the maritime pine that grows exclusively along the coast of southwest France. In the Pycnogenol-treated group, blood sugar levels were significantly lowered as compared to those not on Pycnogenol. The flesh of the grape contains approximately 1/20th-1/100th of the total antioxidant capacity of the seed or the skin. A good-quality study was conducted in 77 diabetic patients who received their standard antidiabetic treatment along with 100 mg Pycnogenol a day or placebo for 12 weeks. The authors attributed the negative results to the short duration of treatment and the low dosages of drug or Pycnogenol. Therefore, those who have autoimmune conditions could see their symptoms increase after taking it., Since Pycnogenol is used for so many conditions, doses can vary. In addition to OPC, grape seed extract contains linoleic acid, flavonoids and phenolic procyanidins that help protect and strengthen capillaries, blood vessels, veins and arteries, which can then improve blood circulation. If you choose to use Pycnogenol, follow the dosage instructions on the label. Additionally, the results showed that the extract has significant anti-pseudomonas activity, making it a potential natural remedy and possible preventive measure for infections. The combination of Panax ginseng and vitamin E also appears to have an effect. Quality and active ingredients in supplements may vary widely from maker to maker. (5). Posted on Thursday, August 14, 2014 The majority of this article is information obtained from the book "All About DIM" by Michael A. Zeligs, MD and A. Scott Connelly, MD. However, a study of 24 adults with ADHD found that pycnogenol did not improve ADHD symptoms better than placebo. Talk to your own doctor about Pycnogenol if youre interested in using it for your own health. editor, The Gale Encyclopedia of Alternative Medicine, third edition, 2009. This Dr. Axe content is medically reviewed or fact checked to ensure factually accurate information. The information on this website has not been evaluated by the Food & Drug Administration or any other medical body. Since components of Pycnogenol can be modified during digestion and absorption as well as by the liver, diseases that affect the gut or liver may increase or decrease its effects [84]. Low-dose Pycnogenol (30 mg/day) may reduce pain in pregnant women, particularly hip, joint, lower back, groin, and calf cramps in the third trimester [71]. (2017). Masquelier was easily able to create a pine bark extract from materials that were otherwise known as waste. A study of 68 people found that Pycnogenol, started 2 days prior to flying, may reduce the duration of jet lag symptoms [83]. Rare cases of liver disease. . Pycnogenol can help control blood pressure, which helps improve overall heart health. ( 1) 2. In some people lung inflammation is caused by leukotrienes chemicals that are released by the body after a person encounters allergens. According to some researchers, when you take Pycnogenol [8]: Research suggests that Pycnogenol may protect cells in the body against oxidative stress. Furthermore, when CHS was suppressed by 71% with exogenous treatment with cis-urocanic acid, the putative epidermal mediator of photoimmunosuppression, 0.2% Pycnogenol lotion reduced the immunosuppression to 18%. We believe that the most accurate information is found directly in the scientific source. Some pycnogenol supplements are mixed with other antioxidants, such as vitamin C. Pine bark extracts other than pycnogenol are also sold. Upset stomach. 2005-2023 Healthline Media a Red Ventures Company. Pycnogenol; Pycnogenol. Research suggests that taking pycnogenol improves mental function and memory in both young adults and the elderly. The standard dose appears to be 100-200 mg/day. But did you know that pine bark extract, like pine oil, is one of natures super antioxidants? New research shows . Pycnogenol is the US trademarked name for an antioxidant made from Mediterranean tree bark. Pycnogenol is a substance taken from the pine bark of trees found in the southwest region of France. In those treated with Pycnogenol, the edema score was increased by 17.9% versus an increase of 58.3% in the control group. Because of its anti-inflammatory effects, nattokinase has been used to help with pain from arthritis, including that of rheumatoid arthritis. This makes it very hard to set a standard dose. 4 Items . Can Pycnogenol help? It is standardized to contain 65-75% procyanidins, a class of polyphenols and flavonoids like those found in blueberries, wine, grape skin, citrus, and cocoa. Circulation and Jet Lag on Long Flights. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. chronic anal fissure may take more than 6 weeks to heal. Some of the top lutein-rich foods to include in your diet are dark leafy greens like spinach and kale, broccoli . In one study, people with high blood pressure were examined to see how the supplement impacted their blood pressure. Pine bark extract is usually taken by mouth in capsule form. The treatment was four 50 mg capsules of Pycnogenol. According to a study of 11 patients with lupus, pycnogenol may reduce symptoms, inflammation, and oxidative stress [54]. In a study of 77 people with symptoms of Irritable Bowel Syndrome (IBS), Pycnogenol (150 mg/day) improved symptoms and reduced the frequency of attacks [77]. The outcome showed significant healing when compared to those subjects who were not given any drug or remedy, concluding that Pycnogenol may be an effective remedy for healing of surgery-related lesions. Possess Anti-Inflammatory Action. Another highlight of grapes nutrition is the presence of polyphenols, which have been shown to decrease chronic inflammation. Another group of men who took just l-arginine didnt improve [66]. from the bark of the French maritime pine tree. Pycnogenol (100 mg/day) improved menopausal symptoms and quality of life in a clinical trial of 35 women after 8 weeks [68]. A combination supplement (pycnogenol with collagen, coenzyme Q10, and other ingredients) reduced skin aging, elasticity, hydration, and tonicity in a study of 30 women [65]. Ana spent years working with patients who suffer from various mental health issues and chronic health problems. Ac., CYT, 12 Benefits of Ginkgo Biloba (Plus Side Effects & Dosage), Tongkat Ali (Eurycoma longifolia): Everything You Need to Know, reduce blood sugar levels in people with diabetes, are within two weeks of a scheduled surgery, medications, herbs, and supplements that affect the blood or clotting. This bark extract has been around for about 450 years. Our website services, content, and products are for informational purposes only. Pine bark extract can help reduce muscle soreness and may help improve conditions relating to poor circulation, high blood pressure, osteoarthritis, diabetes, ADHD, female reproductive issues, skin, erectile dysfunction, eye disease and sports stamina. It decreased concussion symptoms in 42 student-athletes with a history of sports-related concussions after 6 weeks. So it . Our goal is to not have a single piece of inaccurate information on this website. ( 4) Thus, this powerful extract works as a natural ear infection remedy while improving balance and preventing hearing loss. (9), Related:Top 7 Benefits of Green Tea: The No. Optimal doses of pycnogenol have not been set for any condition. Pycnogenol completely normalized function. New studies show Pycnogenol can prevent or reverse the oxidative damage that produces blood vessel disease 4, metabolic syndrome 20, diabetes 20,24, and neurodegenerative disorders 23,24. You can gradually increase how much you take once you get a better idea of how your body reacts to it. Score one for diabetes control and fewer risk factors for the heart. Diarrhea. A deficiency can cause issues like anemia, stunted growth, heart problems and neural tube defects. A randomized, double-blind, placebo-controlled study of 60 patients aged six to 18 years old, was conducted over three months during which patients were randomly assigned to receive either Pycnogenol or placebo. Pycnogenol may have benefits for heart and artery health. In a third study, 19 men with fertility problems were given 200 mg Pycnogenol daily for 90 days. Learn about all the potential benefits of Pycnogenol and find out which ones are most supported by science. Boost gastrointestinal health. What Are These Tiny Red Spots on My Skin (Petechiae)? This ensures that there is a healthy flow of blood to and from the heart. You can find out your systolic blood pressure by looking at the top number of a blood pressure test. 5. Another clinical trial of 76 people with allergic asthma also suggests that Pycnogenol may reduce IgE antibodies and asthma symptoms [18, 16]. Pycnogenol lowered leukotrienes as well. Seems like it must be pretty amazing, but lets look closer. Most anal fissures heal with home treatment after a few days or weeks. The combination of L-arginine and Pycnogenol may help in erectile dysfunction by boosting nitric oxide, which potentially could improve blood flow in men [66]. Enzogenol, a slightly different pine bark extract, may help improve brain function after mild concussions. Align your health hacks with your genes for optimal health & cognitive function. In this article, well summarize all the potential benefits and the scientific research surrounding pine bark extract and Pycnogenol. (adsbygoogle = window.adsbygoogle || []).push({}); Heart Palpitations at Night: Common Causes and How to Treat, Essential Oils for Cough, Cold and Congestion, Sudden High Blood Pressure: Causes, Symptoms and Prevention Tips, Sore Throat on One Side: 7 Causes and Treatments, Natural Remedies for the Burning Sensation in Your Stomach After Eating, Hibiscus Tea: Health Benefits, Nutrition, Side Effects, and Recipes, Vegetable Oil Substitutes: 5 Healthy Alternatives for Baking, Frying, and More, How to Treat Nausea After Eating Eggs or Chicken, Diarrhea after Eating: Causes and Natural Treatments, Top 11 Homeopathic Remedies for High Blood Pressure, Heavy Breathing: Common Causes and Treatments, Pineapple Juice for Cough: Effective Homemade Cough Remedies, Pain in the Left Temple of the Head: 10 Causes and Treatments. Almost 400 years later, Dr. Jacques Masquelier from France came across Cartiers account and started to look for the active ingredients from the bark of the tree. A new peer-reviewed study, published in the Bratislava Medical Journal, shows that daily supplementation with the natural antioxidant, Pycnogenol, a French maritime pine bark extract, can improve the symptoms of ED.. According to a study of 170 women, low-dose pycnogenol (60 mg/day) may improve menopausal symptoms over 3 months, including night sweats, hot flashes, insomnia and sleep problems [69]. The following purported benefits of Pycnogenol are only supported by limited, low-quality clinical studies. Pycnogenol suppresses inflammation and regulates the production of nitric oxide - a . Pine bark extract may be the perfect treatment since its an antioxidant dynamo. Thirty patients were treated with 150 mg of Pycnogenol a day and the other 10 patients with placebo for a period of two months. View as: Grid List. It seems to lower blood pressure and improve blood flow to the legs. Pycnogenol, an extract of French maritime pine bark, helps the body fight normal aging by supporting vascular health and healthy circulation. However, with the addition of twice-daily Pycnogenol, normal erection increased to 80%, which further increased to 92.5% during the third month on thrice-daily Pycnogenol. Moreover, Pycnogenol treatment led to an increase in sperm count and testosterone levels with lowering of blood pressure and cholesterol levels. Asthma is caused by inflammation in the lungs, which makes it hard to breathe. We all know the power of antioxidants to improve health and thehigh-antioxidant foodswe should eat regularly. Importantly, all studies found that Pycnogenol has to be taken at least 5 weeks before the allergy season in order to see potential benefits, with the best results in those who take it 7-8 weeks ahead. Herbal supplements are not regulated by the Food and Drug Administration (FDA), so they may not be up to the same safety standards as medications that have gone through clinical testing and drug trials. 10 Day Erection Delay Sex Pills. A 2011 study by Dr. G. Belcaro concluded, " Pycnogenol administration was effective for better control of signs and symptoms of allergic asthma and reduced the need for medication". Also, its important to note that some of these studies were funded by Horphag Research, the original developers and exclusive marketers of Pycnogenol. If you take any medications regularly, talk to your doctor before you start using pycnogenol supplements. Pycnogenol is a natural plant extract originating from the bark of the maritime pine that grows along the coast of southwest France and is found to contain a unique combination of procyanidins . However, research on these two groups is limited [71, 15]. A total of 40 patients with retinopathy (damage to the retina part of the eye) from diabetes and other vascular causes were enrolled in one study. Studies have also safely used Pycnogenol in children and during pregnancy. In mice, luteolin prevented inflammation and allergic response in the lungs and nose by inhibiting inflammatory cytokines: IL-4, IL-5, and IL-1 3 []. Dizziness. Pycnogenol is the leading ingredient in Isotonix OPC-3, Market America's best-. The same study showed that a single, 200-mg Pycnogenol dose remained effective over six days in preventing cigarette-induced enhanced platelet aggregation. We are dedicated to providing the most scientifically valid, unbiased, and comprehensive information on any given topic. Pycnogenol may stimulate the immune system. 40 years of research has been dedicated to establishing the safety of Pycnogenol and its benefits for human health. For children with ADHD, research suggests that symptoms start to return after about a month without taking maritime pine, so taking periodic breaks shouldnt make it any less effective. Patients were given 100 milligrams of Pycnogenol, a branded version of pine bark extract, for 12 weeks, with continued anti-diabetic treatment. In contrast, bleeding still occurred in the control group [61]. Its used as a natural supplement for several conditions, including dry skin and ADHD. Pine bark extract offers some amazing benefits since its so high in powerful antioxidants. Pycnogenol (150 mg/day) reduced pain in a study of 100 people with osteoarthritis after 3 months. In 19 smokers, increased platelet aggregation was more significantly reduced by 200 mg than either 10 mg or 100 mg of Pycnogenol. 2005 - 2023 WebMD LLC. Pine bark extract appears to reduce the creation of free radicals, which are molecules linked to several skin conditions. A study of 66 healthy adults found that Pycnogenol may reduce the number of leg cramps experienced [11]. However, its always a good idea to start with a low dose so you can monitor how your body responds. Still, more research is needed to better understand these findings and pine bark extracts role in reducing damage from head trauma. (2012). Pycnogenol seems well-tolerated for use in adults for up to 6 months. Pycnogenol pine bark extracts contain a unique blend of flavonoids whose antioxidant action is over is 50 times more powerful than vitamin E, 20 times more powerful than vitamin C and 16 times more active than grapeseed extracts. If a blood clot blocks the normal blood flow, it is known as thrombosis. Several studies show how Pycnogenol helps block platelet formation and thus helps prevent thrombosis. Ask your doctor for advice. Ana received her MS in Pharmacy from the University of Belgrade. Disclaimer: Results are not guaranteed*** and may vary from person to person***. You may want to start slow, taking smaller amounts, to ensure that your body works well with the OPCs found in pine bark extract. A small 2012 study on postmenopausal women found that pine bark extract improved hydration and elasticity of skin. According to the National Institutes of Health, its safe for adults to take 50 to 450 milligrams of pine bark extract daily for up to one year. DOI: Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, 50 to 450 milligrams of pine bark extract daily, Supplements During Pregnancy: Whats Safe and Whats Not, The ADHD Diet: What Works and What Does Not, Berberine A Powerful Supplement With Many Benefits, The Top Health Benefits of Prunes and Prune Juice, What to Know About Andrographis Supplements: Potential Benefits and Uses, Kerry Boyle D.Ac., M.S., L.Ac., Dipl.

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